Antimicrobial Resistance Markers (AMR) qPCR Reagents
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Antimicrobial Resistance Markers (AMR) qPCR Reagents

Part #: 0011|SKU: AMR-4-04|Category: Reagents
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Highlights

True Blue Bio Antimicrobial Resistance Markers (AMR) qPCR Reagents are designed to enable laboratories to rapidly and accurately detect clinically relevant genetic markers associated with antimicrobial resistance. Built on optimized real-time PCR chemistry, the assay delivers high sensitivity and specificity while integrating seamlessly into routine molecular diagnostic workflows.

By identifying multiple resistance determinants in a single run, the test provides actionable insights into the presence of resistance mechanisms that may impact antimicrobial therapy. This supports informed treatment decisions, promotes appropriate antibiotic selection, and helps reduce the spread of resistant pathogens.

The ready-to-use reagent format minimizes hands-on time and reduces technical variability, ensuring consistent and reproducible results across operators and testing runs. Compatibility with standard real-time PCR platforms allows easy implementation without the need for specialized instrumentation.

Each AMR reagent set is produced under stringent quality control processes, including comprehensive assay validation and lot-to-lot consistency testing. These measures ensure reliable performance, high analytical accuracy, and minimal cross-reactivity, even in complex clinical or environmental samples.

When combined with PCRopsis technology, True Blue Bio AMR qPCR Reagents support flexible workflows, including extraction-free and direct-to-amplification approaches. These options help shorten turnaround times, lower operational costs, and enhance laboratory efficiency while maintaining robust analytical performance and clinical confidence.

Pathogen Coverage- 15

AMR

Class A beta-lactamase resistance (blaSHV)
Class A beta-lactamase resistance (blaTEM)
Class A beta-lactamase resistance (CTX-M-Grp1)
Class B beta-lactamase resistance (blaNDM-1/blaNDM-4/blaNDM-5/blaNDM-7)
Class D beta-lactamase resistance (OXA-48/OXA-51)
Fluoroquinolone resistance (gyrA)
Fluoroquinolone resistance (qnrA/qnrB/qnrS)
Methicillin resistance (mecA)
Sulfonamide resistance (sul1)
Tetracycline resistance (tetB)
Tetracycline resistance (tetM)
Trimethoprim resistance (dfrA1)
Vancomycin resistance (vanA)
Vancomycin resistance (vanB)
Vancomycin resistance (vanM)

Technical Specifications

Formats:

  • 384-well pre-plated plate (full and partial filled options)
  • 96-well pre-plated plate
  • Pre-mixed, multiplexed tubes

Multiplex Mixes:

  • GRM-1 to GRM-8 (with internal control)

Platform Compatibility:

  • Applied Biosystems QuantStudio (v1.5.1+)
  • Applied Biosystems 7500 Fast Dx (SDS v1.4+)
  • Bio-Rad CFX96/CFX384 (Maestro v1.1+)
  • Other open qPCR platforms

For Research Use Only. Not for use in diagnostic procedures